Three years after the zombie virus has gutted the United States of America a team of everyday heroes must transport the only known survivor of the plague from New York to California, where the last functioning viral lab waits for his blood.
Bill Murray worries no one will show up to his TV show due to a massive snowstorm in New York City. Through luck and perseverance, guests arrive at Gotham's Carlyle Hotel to help him - dancing and singing in holiday spirit.
Led by a boy named Ryder, a team of six playful rescue dogs use their individual talents to protect the seaside town of Adventure Bay. The pups are occasionally joined by newer helpers: Cap'n Turbot, Robo-Dog, Everest, and Tracker.